What is L Glutathione Reduced Powder ?
L-Glutathione Reduced Powder (GSH) is one of the most widely used antioxidant ingredients in the global nutraceutical and cosmetic industries. As a naturally occurring tripeptide composed of glutamic acid, cysteine, and glycine, reduced glutathione plays a critical role in cellular detoxification, oxidative stress protection, immune support, and skin health.
For manufacturers of dietary supplements, functional foods, cosmetics, and pharmaceutical intermediates, high-purity L-Glutathione Reduced Powder provides a reliable and scientifically recognized ingredient with strong market demand. Suppliers such as Purea Biological Technology Co., Ltd. provide high-quality glutathione raw materials suitable for bulk industrial applications.

Main active ingredients
The primary functional compound in this product is reduced glutathione (GSH). Depending on the specification, the powder can contain different concentrations suitable for various industrial formulations.
|
Component |
Specification |
Function |
|
L-Glutathione (Reduced Form) |
≥98% or ≥99% |
Powerful antioxidant, detoxification support |
|
Glutamic Acid Residue |
Natural peptide component |
Structural amino acid |
|
Cysteine Residue |
Sulfur-containing amino acid |
Redox activity and antioxidant mechanism |
|
Glycine Residue |
Amino acid component |
Peptide stabilization |
COA
|
Analysis |
Specification |
Result |
|
Physical Description |
|
|
|
Appearance |
White powder |
White powder |
|
Specific optical rotation[α]D20 |
-15.5°~-17.5° |
-16° |
|
Solubility |
Soluble in water |
Soluble in water |
|
Appearance of solution |
Clear and colorless |
Clear and colorless |
|
Chemical Tests |
|
|
|
Identification |
Positive |
Positive |
|
Assay (HPLC) |
98.0%-101.0% |
98.3% |
|
Ash |
0.1% Max |
0.07% |
|
Loss on drying |
0.5% Max |
0.28% |
|
Sulfates |
300.0ppm Max |
<300.0ppm |
|
Ammonium (NH4) |
200.0ppm Max |
<200.0ppm |
|
Chlorides |
200ppm Max |
<200.0ppm |
|
Related Substances |
Gross contamination 2.0% Max |
1.4% |
|
GSSG 1.5% Max |
0.6% |
|
|
Heavy metals |
|
|
|
Lead |
2.0mg/kg Max |
<2.0mg/kg |
|
Arsenic |
2.0mg/kg Max |
<2.0mg/kg |
|
Cadmium |
1.0mg/kg Max |
<1.0mg/kg |
|
Mercury |
0.1mg/kg Max |
<0.1mg/kg |
|
Microbiology Control |
|
|
|
Total plate count |
1,000cfu/g Max |
<1,000cfu/g |
|
Yeast & Mold |
100cfu/g Max |
<100cfu/g |
|
Coli group |
0.3MPN/g Max |
<0.3MPN/g |
|
Conclusion |
Complies with the Standard. |
|
|
General Status |
Non-GMO, ISO Certificated. |
|
|
Packing and Storage |
||
|
Packing: Pack in paper-carton and two plastic-bags inside. |
||
|
Shelf life: 2 year when properly stored. |
||
|
Storage: Store in a well-closed place with constant low temperature and no direct sun light. |
||
Characteristics of L Glutathione Reduced Powder
1. Highly Effective Antioxidant Capacity
The core feature of L-Glutathione Reduced Powder is its powerful antioxidant effect. As reduced glutathione (GSH), its sulfhydryl (-SH) activity can directly scavenge free radicals, hydrogen peroxide, and reactive oxygen species, protecting cells from oxidative stress damage. Simultaneously, it can regenerate other antioxidants such as vitamin C and vitamin E, forming a synergistic antioxidant network, significantly improving the body's overall antioxidant capacity, making it an important molecule for natural cell protection.
2. Supports Detoxification and Liver Health
Reduced glutathione participates in liver detoxification metabolism in the body. It can bind to heavy metals, harmful substances, and drug metabolites, promoting their excretion, thereby reducing the burden on the liver and protecting liver cell function. L-Glutathione Reduced Powder is therefore widely used in liver health products, with significant characteristics of protecting the liver and improving detoxification function.
3. Promotes Skin Whitening and Repair
L-Glutathione Reduced Powder can also improve skin tone by inhibiting melanin production and oxidation, achieving whitening and brightening effects. Simultaneously, it promotes skin cell repair and anti-aging, and has an auxiliary effect on improving dry, fine-lined, and dull skin. It is a commonly used and important active ingredient in beauty and skincare products.
4. Immune Regulation and Cell Protection
L-Glutathione Reduced Powder plays a crucial role in the immune system. It maintains the function of T cells and natural killer cells, enhances the body's resistance, and protects cell membranes and mitochondria through antioxidant effects, preventing cell damage and aging. Long-term supplementation helps maintain overall immune health and improves the body's stress resistance.
5. High Water Solubility and Bioavailability
This powder is usually a white to off-white crystalline powder with good water solubility and high bioavailability, making it easy to add to oral supplements, functional drinks, or cosmetics. Its stability has been optimized through modern manufacturing processes, making it easy to store and transport, while ensuring that its antioxidant activity is maximized during use.
Application of L-Glutathione Reduced Powder
|
Application Field |
Practical Example |
Main Function |
Application Description |
|
Dietary Supplements |
Capsules, tablets, and powdered antioxidant supplements |
Antioxidant protection, detoxification support |
L-Glutathione Reduced Powder is widely used in dietary supplements to help neutralize free radicals, support liver detoxification pathways, and maintain cellular health. It is often combined with vitamin C, NAC, or alpha-lipoic acid in advanced antioxidant formulations. |
|
Functional Beverages |
Beauty drinks, wellness beverages, antioxidant drinks |
Cellular protection, skin health support |
Due to its water solubility, glutathione is suitable for functional beverages designed for skin health, anti-aging, and overall wellness. It is commonly used in ready-to-drink beauty beverages and nutritional drink mixes. |
|
Cosmetic & Skincare Products |
Skin brightening serums, creams, masks |
Skin brightening, anti-aging, antioxidant activity |
In cosmetic formulations, glutathione helps reduce oxidative stress in skin cells and supports a brighter and more even skin tone. It is commonly used in whitening creams, anti-aging serums, and advanced skincare formulations. |
|
Pharmaceutical & Medical Nutrition |
Liver health products, clinical nutrition supplements |
Detoxification support, immune modulation |
Glutathione is used as a functional ingredient in pharmaceutical preparations and medical nutrition products aimed at supporting liver health, immune function, and protection against oxidative damage. |
|
Sports Nutrition |
Recovery supplements, antioxidant sports formulas |
Recovery support, oxidative stress reduction |
Athletes and active individuals use glutathione-containing supplements to help reduce oxidative stress generated during intense physical activity and to support faster recovery. |
|
Functional Food Products |
Nutrition bars, fortified powders, wellness foods |
Antioxidant enhancement, nutritional fortification |
Food manufacturers incorporate glutathione into functional foods to enhance antioxidant capacity and add value to health-focused food products targeting wellness-conscious consumers. |

Production process
High-quality glutathione powder requires advanced biotechnology and strict quality control. Professional ingredient manufacturers such as Purea Biological Technology Co., Ltd. typically follow standardized industrial processes to ensure purity and stability.
1. Microbial Fermentation
The production begins with selected microbial strains capable of synthesizing glutathione efficiently. Fermentation conditions such as temperature, pH, and nutrient supply are precisely controlled to maximize yield.
2. Enzymatic Synthesis
After fermentation, enzymatic reactions help convert precursor amino acids into the glutathione tripeptide structure, increasing product purity.
3. Extraction and Purification
The fermentation broth undergoes multiple purification steps, including:
· Membrane filtration
· Ion-exchange chromatography
· Crystallization
These processes remove impurities and concentrate the active compound.
4. Drying and Powder Processing
Purified glutathione crystals are dried under controlled conditions and milled into a fine, stable powder suitable for industrial formulation.
5. Quality Control and Packaging
Each batch is tested for:
· Purity
· Heavy metals
· Microbial limits
· Moisture content
The final product is packed in food-grade or pharmaceutical-grade packaging to ensure stability during storage and transportation.

FAQ
Q1: What is L-Glutathione Reduced Powder?
A: L-Glutathione Reduced Powder is the biologically active form of glutathione (GSH), a tripeptide composed of glutamic acid, cysteine, and glycine. It acts as a powerful antioxidant in the body and is widely used in dietary supplements, cosmetics, and functional food formulations.
Q2: What purity levels are commonly available for bulk glutathione powder?
A: Most industrial-grade glutathione powders are available in 98% or 99% purity, which are suitable for nutraceutical, cosmetic, and pharmaceutical formulations.
Q3: Is L-Glutathione Reduced Powder water-soluble?
A: Yes. Glutathione is highly soluble in water, making it easy to incorporate into capsules, tablets, powders, beverages, and liquid supplements.
Q4: What are the main applications of glutathione in product development?
A: Glutathione is commonly used in dietary supplements, functional beverages, skincare products, and pharmaceutical preparations, especially for antioxidant support, detoxification, and skin health.
Q5: How should L-Glutathione Reduced Powder be stored?
A: The powder should be stored in a cool, dry place away from direct sunlight and kept in tightly sealed containers to maintain stability and product quality.
How to Find Suppliers of L Glutathione Reduced Powder?
We can find a reliable L Glutathione Reduced Powder supplier by considering factors such as product quality, production process and his factory strength. Purea Biological strictly follows international production standards, our L Glutathione Reduced Powder can guarantee its ingredients and has been supplied to many finished product manufacturers around the world. For distribution, we can provide product small packaging customization services so that retailers can better distribute products in their areas.
If you have more procurement standards or procurement needs, please contact us.Email:sales@pureabio.com
Certifications
Purea Biological Technology Co., Ltd. focuses on plant extracts and biopharmaceuticals, backed by authoritative certifications including ISO9001 and SC. We adhere to global quality standards, implement full-chain quality control, and deliver compliant, reliable products to support overseas partners in food, health products and pharmaceutical fields.

Production Environment
Purea Biological Technology Co., Ltd. boasts a modern production base equipped with advanced equipment and technology. From raw material selection to extraction, separation, and purification, we strictly adhere to standard procedures to ensure the reliable quality of each batch of products. We have extremely strict quality control and a comprehensive quality control system. We rigorously control the quality of raw materials from the source, monitor the entire production process, and use advanced equipment to carefully inspect finished products.

Delivery Methods, Payment Way

Packages

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